About BioSim

BioSim is a Network of Excellence established by the European Commission under its 6th Framework Programme. BioSim was initiated on December 1, 2004. The main objective of the Network is to demonstrate how the use of modern simulation technique through a deeper and more qualitative understanding of the underlying biological, pathological and pharmacological processes can lead to a more rational drug development process, improved treatment procedures, and a reduction in the needs for animal experiments.
With its 26 academic, 10 industrial and 4 regulatory partners, the BioSim Network commands a wide range of biomedical expertise. At the same time, the network involves leading experts in pharmacokinetics, computer simulation, and complex systems theory. The purpose of the network is to develop in silico simulation models of cellular, physiological and pharmacological processes to provide a deeper understanding of the biological processes and help the pharmaceutical industry maintain its competitive power.
Click on image to download, or here to order folder. Public Website.	Among the projects that the BioSim Network will undertake in the next 18 months are studies of pancreatic hormone release and interactions among pancreatic cells, protein phosphorylation in human fat cells, flux control and metabolism in striated muscle cells, calcium-induces calcium release and activation of smooth muscle cells, autonomous oscillations in nerve cells and the use of deep brain stimulation to desynchronize cellular spiking behavior, nephron pressure and flow regulation, cardiac arrhythmia, mental disorders and sleep-wake cycles, the function of new anti-cancer molecules, drug absorption and metabolism, insulin-glucose regulation and the treatment of diabetes, chronotherapy of cancer, and the building of virtual populations of relevance to pharmacokinetic studies.
	BioSim will also engage in a wide range of educational activities, including the training of PhD students, specialized courses for industry and regulatory experts, and communication with the public.